Bruker NMR iProbe HR-Liquids, User Manual, Page: 17 / 56

Design and Function
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5 Design and Function
5.1 Overview
The Bruker iProbe is a high-resolution NMR probe for measuring NMR samples in a
spectrometer. The iProbe can only be operated when installed in a magnet, as described
within this manual. Operating the iProbe outside the magnet is not permitted.
The ATMA (automatic Tuning & Matching) unit is integrated in the iProbe, therefore no extra
unit has to be installed. Please refer to the section
ATMA [ } 29] .
The following diagrams show the connections for the different applications of the iProbe and
the necessary infrastructure around the magnet.
Setup with iProbe HR-Liquids
Figure 5.1: Diagram of a setup with iProbe HR-Liquids
Setup with iProbe HR-MAS
High Resolution Magic Angle Spinning (HR-MAS) is a technique for the analysis of samples
with inhomogeneous magnetic susceptibilities, like, for example, semi-solids, gels, or tissues.
By spinning at the magic angle, line broadening effects due to dipolar interactions and
susceptibility differences within the sample are removed resulting in high resolution quality
spectra.
HR-MAS probes are configured with a Z-gradient aligned along the magic angle enabling the
researcher to access a wide variety of NMR experimental techniques including gradient
enhanced solvent suppression and artifact free 2D homo-nuclear and hetero-nuclear
experiments.