Biotage ELSD-1080, Operation Manual

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Biotage ELSD-1080
3.5.6 Method Editor-Downloading Method Sets
To download a Method Set to the ELSD-1080, open the desired
Method Set to be downloaded.
f
Ensure the Method Editor is configured for the correct
communication port for the detector.
f
Ensure that any software session that is currently
accessing the detector via the selected COM port is
closed down.
f
Select the DOWNLOAD button to send the methods to
the ELSD.
If the download was successful, you will see a dialog saying:
"ELS Updated OK".
If the download was unsuccessful, you will see the following
dialog:
In this case, check that the detector is connected to the PC, is
switched on, and the service switch is in the up position (RUN).
A comprehensive guide on how to use the Method Editor
program can be found in the on-line help supplied with the
software
3.6 Controlling the Biotage ELSD-1080 Detector
During an Injection
The Biotage ELSD-1080 detector has the capability to change
operational parameters in real-time, during a sample injection,
using an on-board timetable.
3.6.1 Real-time Operation
The Biotage ELSD-1080 detector can store in memory a series
of time-based events, within a single timetable. This timetable
allows the operational settings of the ELSD to be changed in
real-time during a run.
The temperatures, gas flow, LED, gain and smoothing
parameters can all be configured within this timetable to
change during a sample injection.
The timetable can be used to program the gas flow, in order to
compensate for the change in ELSD response across a solvent
gradient. Alternatively, the timetable can be customized to
create adjustable LED intensities across a sample injection for
mixtures containing samples with wide concentration ranges.
3.6.2 Starting & Stopping Real-time Control
The ELSD-1080 contains an internal timer to initiate the
time-based events stored within the timetable. To start the
40 Publication date: July 2010