Beckman Coulter CEQ 8000, User Manual

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CEQuence Investigator Module
User’s Guide 85
CEQuence Investigator Module
CEQuence Investigator is a module used for comparing sequences to known reference
sequences. For each comparison, one or two new sequence results, in either
orientation, are used to form a consensus for the comparison. The software
automatically determines and matches the orientation of the sequences, forms the
consensus, aligns the consensus with the reference sequence, and provides a detailed
report of the differences.
A number of tools are provided for inspecting and editing the data before the final
report is generated. The Navigator Toolbar allows you to jump to points of interest,
from specific base sequences to a variety of discrepancies in the aligned data set. The
Discrepancy Map provides an overview of the coverage of the reference sequence by
the sequence(s) and indicates the locations of the discrepancies. Together, these
alignment, inspection, editing and reporting features make CEQuence Investigator an
ideal tool for identifying mutations or polymorphisms in DNA.
Figure 48: Main Menu, Sequence Investigator Icon