Angioscan Electronics AngioScan-01, User Manual, Page: 52 / 119

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© 2014 AngioScan-Electronics LLC
AngioScan Medical Tests
4.2.3.2 Occlusion index by pulse wave amplitude
By monitoring the pulse wave amplitude before and after occlusion, the change in the blood volume in
the fingertip can be estimated.
In order to calculate the occlusion index by pulse wave amplitude, a correction to the change in the
amplitude of the reference channel is made. The physiological significance of this occlusion index is to
assess endothelial function in small resistive arteries and arterioles. When the endothelial function is
normal, this value is higher than 2, indicating that more than a two-fold increase in the pulse wave
amplitude was induced by occlusion.
In the example below, a more than three-fold (3.3) increase in the pulse wave amplitude was observed.
The occlusion index takes into account the changes in the pulse wave amplitude in the reference
channel.