Agilent Technologies
Agilent G2721AA Spectrum Mill
MS Proteomics Workbench
Quick Start Guide
A guide to the Spectrum Mill workbench
Use this reference for your first steps with the Spectrum Mill workbench.
What is the Spectrum Mill MS Proteomics Workbench?
The Spectrum Mill software is a collection of tools for high-
throughput processing of MS and MS/MS spectra to provide protein
and peptide identifications and relative quantitation. The
Spectrum Mill workbench can do in minutes what could take you
hours or days to do manually.
This software includes bioinformatics tools for:
•
Spectral preprocessing for MS/MS and MS-only data, including
spectral quality filtering and precursor charge state assignment
for MS/MS spectra
•
Protein database search, including searches for both MS/MS and
MS-only spectra
•
Data review, validation, and comparison for large data sets,
including those from two-dimensional LC/MS/MS analyses and
differential expression studies
•
De novo
sequencing
•
Identification of mutations, post-translational modifications,
and chemical modifications
•
Differential expression quantitation
The Spectrum Mill workbench accepts Agilent data, as well as data
from other vendors’ mass spectrometers. The software executes on
a web server, and you access the program via a web browser
window.
